LOCUS       XM_047434138            6378 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily C member 1
            (ABCC1 blood group) (ABCC1), transcript variant X10, mRNA.
ACCESSION   XM_047434138
VERSION     XM_047434138.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000016.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6378
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="16"
     gene            1..6378
                     /gene="ABCC1"
                     /gene_synonym="ABC29; ABCC; DFNA77; GS-X; MRP; MRP1"
                     /note="ATP binding cassette subfamily C member 1 (ABCC1
                     blood group); Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 2 mRNAs, 36 ESTs, 739 long SRA
                     reads, 6 Proteins, and 99% coverage of the annotated
                     genomic feature by RNAseq alignments, including 22 samples
                     with support for all annotated introns"
                     /db_xref="GeneID:4363"
                     /db_xref="HGNC:HGNC:51"
                     /db_xref="MIM:158343"
     CDS             137..4606
                     /gene="ABCC1"
                     /gene_synonym="ABC29; ABCC; DFNA77; GS-X; MRP; MRP1"
                     /codon_start=1
                     /product="multidrug resistance-associated protein 1
                     isoform X10"
                     /protein_id="XP_047290094.1"
                     /db_xref="GeneID:4363"
                     /db_xref="HGNC:HGNC:51"
                     /db_xref="MIM:158343"
                     /translation="MALRGFCSADGSDPLWDWNVTWNTSNPDFTKCFQNTVLVWVPCF
                     YLWACFPFYFLYLSRHDRGYIQMTPLNKTKTALGFLLWIVCWADLFYSFWERSRGIFL
                     APVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLVALVCALAILRSKIMTA
                     LKENPCPESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKN
                     WKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKSPQKEWNPSLFKVLY
                     KTFGPYFLMSFFFKAIHDLMMFSGPQILKLLIKFVNDTKAPDWQGYFYTVLLFVTACL
                     QTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRF
                     MDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMVLMVPVNAVMAMKTKTYQV
                     AHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLSAVGT
                     FTWVCTPFLVALCTFAVYVTIDENNILDAQTAFVSLALFNILRFPLNILPMVISSIVQ
                     ASVSLKRLRIFLSHEELEPDSIERRPVKDGGGTNSITVRNATFTWARSDPPTLNGITF
                     SIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRE
                     NILFGCQLEEPYYRSVIQACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAV
                     YSNADIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRILVTHSMSYLPQVDVIIV
                     MSGGKISEMGSYQELLARDGAFAEFLRTYASTEQEQDAEENGVTGVSGPGKEAKQMEN
                     GMLVTDSAGKQLQRQLSSSSSYSGDISRHHNSTAELQKAEAKKEETWKLMEADKAQTG
                     QVKLSVYWDYMKAIGLFISFLSIFLFMCNHVSALASNYWLSLWTDDPIVNGTQEHTKV
                     RLSVYGALGISQGIAVFGYSMAVSIGGILASRCLHVDLLHSILRSPMSFFERTPSGNL
                     VNRFSKELDTVDSMIPEVIKMFMGSLFNVIGACIVILLATPIAAIIIPPLGLIYFFVQ
                     RFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIHQSDLKVDENQKA
                     YYPSIVANRWLAVRLECVGNCIVLFAALFAVISRHSLSAGLVGLSVSYSLQVTTYLNW
                     LVRMSSEMETNIVAVERLKEYSETEKEAPWQIQETAPPSSWPQVGRVEFRNYCLRYRE
                     DLDFVLRHINVTINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGINIAKIG
                     LHDLRFKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSALPDKLD
                     HECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFED
                     CTVLTIAHRLNTIMDYTRVIVLDKGEIQEYGAPSDLLQQRGLFYSMAKDAGLV"
ORIGIN      
        1 gccgccgccg ccgccgccag cgctagcgcc agcagccggg cccgatcacc cgccgcccgg
       61 tgcccgccgc cgcccgcgcc agcaaccggg cccgatcacc cgccgcccgg tgcccgccgc
      121 cgcccgcgcc accggcatgg cgctccgggg cttctgcagc gccgatggct ccgacccgct
      181 ctgggactgg aatgtcacgt ggaataccag caaccccgac ttcaccaagt gctttcagaa
      241 cacggtcctc gtgtgggtgc cttgttttta cctctgggcc tgtttcccct tctacttcct
      301 ctatctctcc cgacatgacc gaggctacat tcagatgaca cctctcaaca aaaccaaaac
      361 tgccttggga tttttgctgt ggatcgtctg ctgggcagac ctcttctact ctttctggga
      421 aagaagtcgg ggcatattcc tggccccagt gtttctggtc agcccaactc tcttgggcat
      481 caccatgctg cttgctacct ttttaattca gctggagagg aggaagggag ttcagtcttc
      541 agggatcatg ctcactttct ggctggtagc cctagtgtgt gccctagcca tcctgagatc
      601 caaaattatg acagccttaa aagagaatcc ctgcccagag tccagcgctt ccttcctgtc
      661 gaggatcacc ttctggtgga tcacagggtt gattgtccgg ggctaccgcc agcccctgga
      721 gggcagtgac ctctggtcct taaacaagga ggacacgtcg gaacaagtcg tgcctgtttt
      781 ggtaaagaac tggaagaagg aatgcgccaa gactaggaag cagccggtga aggttgtgta
      841 ctcctccaag gatcctgccc agccgaaaga gagttccaag gtggatgcga atgaggaggt
      901 ggaggctttg atcgtcaagt ccccacagaa ggagtggaac ccctctctgt ttaaggtgtt
      961 atacaagacc tttgggccct acttcctcat gagcttcttc ttcaaggcca tccacgacct
     1021 gatgatgttt tccgggccgc agatcttaaa gttgctcatc aagttcgtga atgacacgaa
     1081 ggccccagac tggcagggct acttctacac cgtgctgctg tttgtcactg cctgcctgca
     1141 gaccctcgtg ctgcaccagt acttccacat ctgcttcgtc agtggcatga ggatcaagac
     1201 cgctgtcatt ggggctgtct atcggaaggc cctggtgatc accaattcag ccagaaaatc
     1261 ctccacggtc ggggagattg tcaacctcat gtctgtggac gctcagaggt tcatggactt
     1321 ggccacgtac attaacatga tctggtcagc ccccctgcaa gtcatccttg ctctctacct
     1381 cctgtggctg aatctgggcc cttccgtcct ggctggagtg gcggtgatgg tcctcatggt
     1441 gcccgtcaat gctgtgatgg cgatgaagac caagacgtat caggtggccc acatgaagag
     1501 caaagacaat cggatcaagc tgatgaacga aattctcaat gggatcaaag tgctaaagct
     1561 ttatgcctgg gagctggcat tcaaggacaa ggtgctggcc atcaggcagg aggagctgaa
     1621 ggtgctgaag aagtctgcct acctgtcagc cgtgggcacc ttcacctggg tctgcacgcc
     1681 ctttctggtg gccttgtgca catttgccgt ctacgtgacc attgacgaga acaacatcct
     1741 ggatgcccag acagccttcg tgtctttggc cttgttcaac atcctccggt ttcccctgaa
     1801 cattctcccc atggtcatca gcagcatcgt gcaggcgagt gtctccctca aacgcctgag
     1861 gatctttctc tcccatgagg agctggaacc tgacagcatc gagcgacggc ctgtcaaaga
     1921 cggcgggggc acgaacagca tcaccgtgag gaatgccaca ttcacctggg ccaggagcga
     1981 ccctcccaca ctgaatggca tcaccttctc catccccgaa ggtgctttgg tggccgtggt
     2041 gggccaggtg ggctgcggaa agtcgtccct gctctcagcc ctcttggctg agatggacaa
     2101 agtggagggg cacgtggcta tcaagggctc cgtggcctat gtgccacagc aggcctggat
     2161 tcagaatgat tctctccgag aaaacatcct ttttggatgt cagctggagg aaccatatta
     2221 caggtccgtg atacaggcct gtgccctcct cccagacctg gaaatcctgc ccagtgggga
     2281 tcggacagag attggcgaga agggcgtgaa cctgtctggg ggccagaagc agcgcgtgag
     2341 cctggcccgg gccgtgtact ccaacgctga catttacctc ttcgatgatc ccctctcagc
     2401 agtggatgcc catgtgggaa aacacatctt tgaaaatgtg attggcccca aggggatgct
     2461 gaagaacaag acgcggatct tggtcacgca cagcatgagc tacttgccgc aggtggacgt
     2521 catcatcgtc atgagtggcg gcaagatctc tgagatgggc tcctaccagg agctgctggc
     2581 tcgagacggc gccttcgctg agttcctgcg tacctatgcc agcacagagc aggagcagga
     2641 tgcagaggag aacggggtca cgggcgtcag cggtccaggg aaggaagcaa agcaaatgga
     2701 gaatggcatg ctggtgacgg acagtgcagg gaagcaactg cagagacagc tcagcagctc
     2761 ctcctcctat agtggggaca tcagcaggca ccacaacagc accgcagaac tgcagaaagc
     2821 tgaggccaag aaggaggaga cctggaagct gatggaggct gacaaggcgc agacagggca
     2881 ggtcaagctt tccgtgtact gggactacat gaaggccatc ggactcttca tctccttcct
     2941 cagcatcttc cttttcatgt gtaaccatgt gtccgcgctg gcttccaact attggctcag
     3001 cctctggact gatgacccca tcgtcaacgg gactcaggag cacacgaaag tccggctgag
     3061 cgtctatgga gccctgggca tttcacaagg gatcgccgtg tttggctact ccatggccgt
     3121 gtccatcggg gggatcttgg cttcccgctg tctgcacgtg gacctgctgc acagcatcct
     3181 gcggtcaccc atgagcttct ttgagcggac ccccagtggg aacctggtga accgcttctc
     3241 caaggagctg gacacagtgg actccatgat cccggaggtc atcaagatgt tcatgggctc
     3301 cctgttcaac gtcattggtg cctgcatcgt tatcctgctg gccacgccca tcgccgccat
     3361 catcatcccg ccccttggcc tcatctactt cttcgtccag aggttctacg tggcttcctc
     3421 ccggcagctg aagcgcctcg agtcggtcag ccgctccccg gtctattccc atttcaacga
     3481 gaccttgctg ggggtcagcg tcattcgagc cttcgaggag caggagcgct tcatccacca
     3541 gagtgacctg aaggtggacg agaaccagaa ggcctattac cccagcatcg tggccaacag
     3601 gtggctggcc gtgcggctgg agtgtgtggg caactgcatc gttctgtttg ctgccctgtt
     3661 tgcggtgatc tccaggcaca gcctcagtgc tggcttggtg ggcctctcag tgtcttactc
     3721 attgcaggtc accacgtact tgaactggct ggttcggatg tcatctgaaa tggaaaccaa
     3781 catcgtggcc gtggagaggc tcaaggagta ttcagagact gagaaggagg cgccctggca
     3841 aatccaggag acagctccgc ccagcagctg gccccaggtg ggccgagtgg aattccggaa
     3901 ctactgcctg cgctaccgag aggacctgga cttcgttctc aggcacatca atgtcacgat
     3961 caatggggga gaaaaggtcg gcatcgtggg gcggacggga gctgggaagt cgtccctgac
     4021 cctgggctta tttcggatca acgagtctgc cgaaggagag atcatcatcg atggcatcaa
     4081 catcgccaag atcggcctgc acgacctccg cttcaagatc accatcatcc cccaggaccc
     4141 tgttttgttt tcgggttccc tccgaatgaa cctggaccca ttcagccagt actcggatga
     4201 agaagtctgg acgtccctgg agctggccca cctgaaggac ttcgtgtcag cccttcctga
     4261 caagctagac catgaatgtg cagaaggcgg ggagaacctc agtgtcgggc agcgccagct
     4321 tgtgtgccta gcccgggccc tgctgaggaa gacgaagatc cttgtgttgg atgaggccac
     4381 ggcagccgtg gacctggaaa cggacgacct catccagtcc accatccgga cacagttcga
     4441 ggactgcacc gtcctcacca tcgcccaccg gctcaacacc atcatggact acacaagggt
     4501 gatcgtcttg gacaaaggag aaatccagga gtacggcgcc ccatcggacc tcctgcagca
     4561 gagaggtctt ttctacagca tggccaaaga cgccggcttg gtgtgagccc cagagctggc
     4621 atatctggtc agaactgcag ggcctatatg ccagcgccca gggaggagtc agtacccctg
     4681 gtaaaccaag cctcccacac tgaaaccaaa acataaaaac caaacccaga caaccaaaac
     4741 atattcaaag cagcagccac cgccatccgg tcccctgcct ggaactggct gtgaagaccc
     4801 aggagagaca gagatgcgaa ccacccaaaa cacgcacacc ctgcccctgg tgccctgaga
     4861 cagacacaca gcctcacgcc cccaggaatg caagtggttt cctggtgctt cccacggagg
     4921 agttttggca gccagacttc tggaggaatt ggttgtatag aagatcctag tgaccaaatt
     4981 cagcctactg cctcggatct ctccagccga agtctgtgga ctgcaagtct ttgagatgct
     5041 tctggctccc atcacctcta acatccttgt ctgggtctac caggaacgct tcatttcctt
     5101 ggggctgcag ttttgtggtt gaggggcctg gagaaaatca ttttctcccc ttggcagtgt
     5161 cccagggccc tggatggtcc tcttaccaac atctggtctt ccaggcactc aaaagctggg
     5221 aaccagcatc tcagcgccag ctctaccagt tctcgttttg ggccagaggc agcctctgca
     5281 ctcccacgcc tgtcctcctg gaagggacct ggttggacta acggctaacc tggacctgga
     5341 actgtagggc caggggattg tctcagggcc gacgttccac ctggggcttc cctccccacc
     5401 caccccgact ccaggctttc ccttttttct tttgttcaac attgtaagaa caatcaatgc
     5461 tgttattact gttcccacca tgattgatgt ggggtaaata ttaaggagat ggcctcatgg
     5521 gaatttgacc ttgactagaa atagagactg agagtgagca accagctgga aggtactatg
     5581 ccagtcctag cagaaaaatg tgttaggggc ctggcccaaa gcagtgttgg ttgcttacag
     5641 tgttgattga ttttgttctt ttttcttacc acctcttttc tttccctctc atggtacctg
     5701 ctcatggtta tgaagctttc aaagtaaaga acacgaaata cctcccaagt attaccagtg
     5761 ggtaccaaaa aaatgtcccc ttgagtcttt tccttgtttt tagatgttaa ttctctccct
     5821 tggcatccgg ttagcccccc agggggggca gcattgtgga gaacttgata tttagttact
     5881 gatgctcttc caggacacga aaagaaccca tctttgaata tcaatgattt ttttttttta
     5941 agtactgttc cggggagaaa aacagtctca aaacttgaac ttcttgggaa tagaagtgtt
     6001 gggctgagaa gtaacattcc caggaaatag tgagaagctc gccctgtgtt tgaaaccgtg
     6061 ttggtctctg tgttcctgga agaaaacagg gaagcagcat cttttaaagc ctgttcttta
     6121 aggtgtctcg ttagagccca aagtggaatc cggaaggcag ccagagctga ggctgcccca
     6181 agactcagac ttgctaagaa ttacgccgcc gacttcaaac ccagagagca tctttctttt
     6241 aggcgaaaac gcatatattt attttttgta agttatacca ttctttcaca ttagataaac
     6301 taagttttgg gggatccttt tgtaatgact tacactggaa atgcgaacat ttgcagtaaa
     6361 aaaatatata tatatcta
//
