LOCUS       XM_017005167            2993 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily B member 11
            (ABCB11), transcript variant X6, mRNA.
ACCESSION   XM_017005167
VERSION     XM_017005167.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000002.12) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017005167.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2993
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="2"
     gene            1..2993
                     /gene="ABCB11"
                     /gene_synonym="ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4;
                     SPGP"
                     /note="ATP binding cassette subfamily B member 11; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 14 ESTs, 2 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 2 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:8647"
                     /db_xref="HGNC:HGNC:42"
                     /db_xref="MIM:603201"
     CDS             197..2947
                     /gene="ABCB11"
                     /gene_synonym="ABC16; BRIC2; BSEP; PFIC-2; PFIC2; PGY4;
                     SPGP"
                     /codon_start=1
                     /product="bile salt export pump isoform X6"
                     /protein_id="XP_016860656.1"
                     /db_xref="GeneID:8647"
                     /db_xref="HGNC:HGNC:42"
                     /db_xref="MIM:603201"
                     /translation="MSEDGYKLDRIKGEIEFHNVTFHYPSRPEVKILNDLNMVIKPGE
                     MTALVGPSGAGKSTALQLIQRFYDPCEGMVTVDGHDIRSLNIQWLRDQIGIVEQEPVL
                     FSTTIAENIRYGREDATMEDIVQAAKEANAYNFIMDLPQQFDTLVGEGGGQMSGGQKQ
                     RVAIARALIRNPKILLLDMATSALDNESEAMVQEVLSKIQHGHTIISVAHRLSTVRAA
                     DTIIGFEHGTAVERGTHEELLERKGVYFTLVTLQSQGNQALNEEDIKDATEDDMLART
                     FSRGSYQDSLRASIRQRSKSQLSYLVHEPPLAVVDHKSTYEEDRKDKDIPVQEEVEPA
                     PVRRILKFSAPEWPYMLVGSVGAAVNGTVTPLYAFLFSQILGTFSIPDKEEQRSQING
                     VCLLFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPG
                     ALTTRLATDASQVQGAAGSQIGMIVNSFTNVTVAMIIAFSFSWKLSLVILCFFPFLAL
                     SGATQTRMLTGFASRDKQALEMVGQITNEALSNIRTVAGIGKERRFIEALETELEKPF
                     KTAIQKANIYGFCFAFAQCIMFIANSASYRYGGYLISNEGLHFSYVFRVISAVVLSAT
                     ALGRAFSYTPSYAKAKISAARFFQLLDRQPPISVYNTAGEKWDNFQGKIDFVDCKFTY
                     PSRPDSQVLNGLSVSISPGQTLAFVGSSGCGKSTSIQLLERFYDPDQGKVMIDGHDSK
                     KVNVQFLRSNIGIVSQEPVLFACSIMDNIKYGDNTKEIPMERVIAAAKQAQLHDFVMS
                     LPEKYETNVGSQGSQLSRGEKQRIAIARAIVRDPKILLLDEATSALDTESEKTVQVAL
                     DKAREGRTCIVIAHRLSTIQNADIIAVMAQGVVIEKGTHEELMAQKGAYYKLVTTGSP
                     IS"
ORIGIN      
        1 ggcacaatct cggctcactg caaccccctc ctcccaggtt caagcgattc tcctgcctca
       61 agggagtgaa tgcaacaggg aactagaaca agtaagaccc ctgttcttta ctcatgctgg
      121 gagaggacag gcagtaaaga agtatgcaca ttcaaagata agacaatagc agagagtgaa
      181 acccatcatt gactgcatgt cagaagatgg ttacaagttg gatcgaatca agggtgaaat
      241 tgaattccat aatgtgacct tccattatcc ttccagacca gaggtgaaga ttctaaatga
      301 cctcaacatg gtcattaaac caggggaaat gacagctctg gtaggaccca gtggagctgg
      361 aaaaagtaca gcactgcaac tcattcagcg attctatgac ccctgtgaag gaatggtgac
      421 cgtggatggc catgacattc gctctcttaa cattcagtgg cttagagatc agattgggat
      481 agtggagcaa gagccagttc tgttctctac caccattgca gaaaatattc gctatggcag
      541 agaagatgca acaatggaag acatagtcca agctgccaag gaggccaatg cctacaactt
      601 catcatggac ctgccacagc aatttgacac ccttgttgga gaaggaggag gccagatgag
      661 tggtggccag aaacaaaggg tagctatcgc cagagccctc atccgaaatc ccaagattct
      721 gcttttggac atggccacct cagctctgga caatgagagt gaagccatgg tgcaagaagt
      781 gctgagtaag attcagcatg ggcacacaat catttcagtt gctcatcgct tgtctacggt
      841 cagagctgca gataccatca ttggttttga acatggcact gcagtggaaa gagggaccca
      901 tgaagaatta ctggaaagga aaggtgttta cttcactcta gtgactttgc aaagccaggg
      961 aaatcaagct cttaatgaag aggacataaa ggatgcaact gaagatgaca tgcttgcgag
     1021 gacctttagc agagggagct accaggatag tttaagggct tccatccggc aacgctccaa
     1081 gtctcagctt tcttacctgg tgcacgaacc tccattagct gttgtagatc ataagtctac
     1141 ctatgaagaa gatagaaagg acaaggacat tcctgtgcag gaagaagttg aacctgcccc
     1201 agttaggagg attctgaaat tcagtgctcc agaatggccc tacatgctgg tagggtctgt
     1261 gggtgcagct gtgaacggga cagtcacacc cttgtatgcc tttttattca gccagattct
     1321 tgggactttt tcaattcctg ataaagagga acaaaggtca cagatcaatg gtgtgtgcct
     1381 actttttgta gcaatgggct gtgtatctct tttcacccaa tttctacagg gatatgcctt
     1441 tgctaaatct ggggagctcc taacaaaaag gctacgtaaa tttggtttca gggcaatgct
     1501 ggggcaagat attgcctggt ttgatgacct cagaaatagc cctggagcat tgacaacaag
     1561 acttgctaca gatgcttccc aagttcaagg ggctgccggc tctcagatcg ggatgatagt
     1621 caattccttc actaacgtca ctgtggccat gatcattgcc ttctccttta gctggaagct
     1681 gagcctggtc atcttgtgct tcttcccctt cttggcttta tcaggagcca cacagaccag
     1741 gatgttgaca ggatttgcct ctcgagataa gcaggccctg gagatggtgg gacagattac
     1801 aaatgaagcc ctcagtaaca tccgcactgt tgctggaatt ggaaaggaga ggcggttcat
     1861 tgaagcactt gagactgagc tggagaagcc cttcaagaca gccattcaga aagccaatat
     1921 ttacggattc tgctttgcct ttgcccagtg catcatgttt attgcgaatt ctgcttccta
     1981 cagatatgga ggttacttaa tctccaatga ggggctccat ttcagctatg tgttcagggt
     2041 gatctctgca gttgtactga gtgcaacagc tcttggaaga gccttctctt acaccccaag
     2101 ttatgcaaaa gctaaaatat cagctgcacg cttttttcaa ctgctggacc gacaaccccc
     2161 aatcagtgta tacaatactg caggtgaaaa atgggacaac ttccagggga agattgattt
     2221 tgttgattgt aaatttacat atccttctcg acctgactcg caagttctga atggtctctc
     2281 agtgtcgatt agtccagggc agacactggc gtttgttggg agcagtggat gtggcaaaag
     2341 cactagcatt cagctgttgg aacgtttcta tgatcctgat caagggaagg tgatgataga
     2401 tggtcatgac agcaaaaaag taaatgtcca gttcctccgc tcaaacattg gaattgtttc
     2461 ccaggaacca gtgttgtttg cctgtagcat aatggacaat atcaagtatg gagacaacac
     2521 caaagaaatt cccatggaaa gagtcatagc agctgcaaaa caggctcagc tgcatgattt
     2581 tgtcatgtca ctcccagaga aatatgaaac taacgttggg tcccaggggt ctcaactctc
     2641 tagaggggag aaacaacgca ttgctattgc tcgggccatt gtacgagatc ctaaaatctt
     2701 gctactagat gaagccactt ctgccttaga cacagaaagt gaaaagacgg tgcaggttgc
     2761 tctagacaaa gccagagagg gtcggacctg cattgtcatt gcccatcgct tgtccaccat
     2821 ccagaacgcg gatatcattg ctgtcatggc acagggggtg gtgattgaaa aggggaccca
     2881 tgaagaactg atggcccaaa aaggagccta ctacaaacta gtcaccactg gatcccccat
     2941 cagttgaccc aatgcaagaa tctcagacac acatgacgca ccagttacag ggg
//
