LOCUS       XM_047438056            4040 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily A member 7
            (ABCA7), transcript variant X21, mRNA.
ACCESSION   XM_047438056
VERSION     XM_047438056.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4040
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..4040
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /note="ATP binding cassette subfamily A member 7; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 34 ESTs, 62 long SRA reads, 1 Protein, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 8 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
     CDS             228..3956
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /codon_start=1
                     /product="phospholipid-transporting ATPase ABCA7 isoform
                     X14"
                     /protein_id="XP_047294012.1"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
                     /translation="MAFWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRH
                     SHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQLTPGEEPGRLSNFNDSLV
                     SRLLADARTVLGGASAHRTLAGLGKLIATLRAARSTAQPQPTKQSPLEPPMLDVAELL
                     TSLLRTESLGLALGQAQEPLHSLLEAAEDLAQELLALRSLVELRALLQRPRGTSGPLE
                     LLSEALCSVRGPSSTVGPSLNWYEASDLMELVGQEPESALPDSSLSPACSELIGALDS
                     HPLSRLLWRRLKPLILGKLLFAPDTPFTRKLMAQVNRTFEELTLLRDVREVWEMLGPR
                     IFTFMNDSSNVAMLQRLLQMQDEGRRQPRPGGRDHMEALRSFLDPGSGGYSWQDAHAD
                     VGHLVGTLGRVTECLSLDKLEAAPSEAALVSRALQLLAEHRFWAGVVFLGPEDSSDPT
                     EHPTPDLGPGHVRIKIRMDIDVVTRTNKIRDRFWDPGPAADPLTDLRYVWGGFVYLQD
                     LVERAAVRVLSGANPRAGLYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTLTV
                     KAVVREKETRLRDTMRAMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSH
                     PGVVFLFLAAFAVATVTQSFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLP
                     AGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADVFSLAQVSGLLLLD
                     AALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYWCGPRPPKSPAPCPTPLDPKVLVEE
                     APPGLSPGVSVRSLEKRFPGSPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSG
                     LFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLKGLSAA
                     VVGPEQDRLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDP
                     ASRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLG
                     SGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPG
                     ARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKV
                     VEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSG
                     PDAVGRVQGWALTRQQLQALLLKRFLLARRSRRGLFAQ"
ORIGIN      
        1 aagctcagcg cacttggctt aaggggcggc gcgctccctg cctgctgctg ggcggaggga
       61 aggcggcaag agctgcggag cccctggaag agcttccagg aaccctgcgc tgtgggataa
      121 aggaatgagg ttcagaaagg ggcagggagt tgcccgcagc cgcaccgcac gtcttcagcc
      181 cgaccgttgt cctgacctct ctgtcccgtc ccctgcccag tctcaccatg gccttctgga
      241 cacagctgat gctgctgctc tggaagaatt tcatgtatcg ccggagacag ccggtccagc
      301 tcctggtcga attgctgtgg cctctcttcc tcttcttcat cctggtggct gttcgccact
      361 cccacccgcc cctggagcac catgaatgcc acttcccaaa caagccactg ccatcggcgg
      421 gcaccgtgcc ctggctccag ggtctcatct gtaatgtgaa caacacctgc tttccgcagc
      481 tgacaccggg cgaggagccc gggcgcctga gcaacttcaa cgactccctg gtctcccggc
      541 tgctagccga tgcccgcact gtgctgggag gggccagtgc ccacaggacg ctggctggcc
      601 tagggaagct gatcgccacg ctgagggctg cacgcagcac ggcccagcct caaccaacca
      661 agcagtctcc actggaacca cccatgctgg atgtcgcgga gctgctgacg tcactgctgc
      721 gcacggaatc cctggggttg gcactgggcc aagcccagga gcccttgcac agcttgttgg
      781 aggccgctga ggacctggcc caggagctcc tggcgctgcg cagcctggtg gagcttcggg
      841 cactgctgca gagaccccga gggaccagcg gccccctgga gttgctgtca gaggccctct
      901 gcagtgtcag gggacctagc agcacagtgg gcccctccct caactggtac gaggctagtg
      961 acctgatgga gctggtgggg caggagccag aatccgccct gccagacagc agcctgagcc
     1021 ccgcctgctc ggagctgatt ggagccctgg acagccaccc gctgtcccgc ctgctctgga
     1081 gacgcctgaa gcctctgatc ctcgggaagc tactctttgc accagataca ccttttaccc
     1141 ggaagctcat ggcccaggtg aaccggacct tcgaggagct caccctgctg agggatgtcc
     1201 gggaggtgtg ggagatgctg ggaccccgga tcttcacctt catgaacgac agttccaatg
     1261 tggccatgct gcagcggctc ctgcagatgc aggatgaagg aagaaggcag cccagacctg
     1321 gaggccggga ccacatggag gccctgcgat cctttctgga ccctgggagc ggtggctaca
     1381 gctggcagga cgcacacgct gatgtggggc acctggtggg cacgctgggc cgagtgacgg
     1441 agtgcctgtc cttggacaag ctggaggcgg caccctcaga ggcagccctg gtgtcgcggg
     1501 ccctgcaact gctcgcggaa catcgattct gggccggcgt cgtcttcttg ggacctgagg
     1561 actcttcaga ccccacagag cacccaaccc cagacctggg ccccggccac gtgcgcatca
     1621 aaatccgcat ggacattgac gtggtcacga ggaccaataa gatcagggac aggttttggg
     1681 accctggccc agccgcggac cccctgaccg acctgcgcta cgtgtggggc ggcttcgtgt
     1741 acctgcaaga cctggtggag cgtgcagccg tccgcgtgct cagcggcgcc aacccccggg
     1801 ccggcctcta cctgcagcag atgccctatc cgtgctatgt ggacgacgtg ttcctgcgtg
     1861 tgctgagccg gtcgctgccg ctcttcctga cgctggcctg gatctactcc gtgacactga
     1921 cagtgaaggc cgtggtgcgg gagaaggaga cgcggctgcg ggacaccatg cgcgccatgg
     1981 ggctcagccg cgcggtgctc tggctaggct ggttcctcag ctgcctcggg cccttcctgc
     2041 tcagcgccgc actgctggtt ctggtgctca agctgggaga catcctcccc tacagccacc
     2101 cgggcgtggt cttcctgttc ttggcagcct tcgcggtggc cacggtgacc cagagcttcc
     2161 tgctcagcgc cttcttctcc cgcgccaacc tggctgcggc ctgcggcggc ctggcctact
     2221 tctccctcta cctgccctac gtgctgtgtg tggcttggcg ggaccggctg cccgcgggtg
     2281 gccgcgtggc cgcgagcctg ctgtcgcccg tggccttcgg cttcggctgc gagagcctgg
     2341 ctctgctgga ggagcagggc gagggcgcgc agtggcacaa cgtgggcacc cggcctacgg
     2401 cagacgtctt cagcctggcc caggtctctg gccttctgct gctggacgcg gcgctctacg
     2461 gcctcgccac ctggtacctg gaagctgtgt gcccaggcca gtacgggatc cctgaaccat
     2521 ggaattttcc ttttcggagg agctactggt gcggacctcg gccccccaag agtccagccc
     2581 cttgccccac cccgctggac ccaaaggtgc tggtagaaga ggcaccgccc ggcctgagtc
     2641 ctggcgtctc cgttcgcagc ctggagaagc gctttcctgg aagcccgcag ccagccctgc
     2701 gggggctcag cctggacttc taccagggcc acatcaccgc cttcctgggc cacaacgggg
     2761 ccggcaagac caccaccctg tccatcttga gtggcctctt cccacccagt ggtggctctg
     2821 ccttcatcct gggccacgac gtccgctcca gcatggccgc catccggccc cacctgggcg
     2881 tctgtcctca gtacaacgtg ctgtttgaca tgctgaccgt ggacgagcac gtctggttct
     2941 atgggcggct gaagggtctg agtgccgctg tagtgggccc cgagcaggac cgtctgctgc
     3001 aggatgtggg gctggtctcc aagcagagtg tgcagactcg ccacctctct ggtgggatgc
     3061 aacggaagct gtccgtggcc attgcctttg tgggcggctc ccaagttgtt atcctggacg
     3121 agcctacggc tggcgtggat cctgcttccc gccgcggtat ttgggagctg ctgctcaaat
     3181 accgagaagg tcgcacgctg atcctctcca cccaccacct ggatgaggca gagctgctgg
     3241 gagaccgtgt ggccgtggtg gcaggtggcc gcttgtgctg ctgtggctcc ccactcttcc
     3301 tgcgccgtca cctgggctcc ggctactacc tgacgctggt gaaggcccgc ctgcccctga
     3361 ccaccaatga gaaggctgac actgacatgg agggcagtgt ggacaccagg caggaaaaga
     3421 agaatggcag ccagggcagc agagtcggca ctcctcagct gctggccctg gtacagcact
     3481 gggtgcccgg ggcacggctg gtggaggagc tgccacacga gctggtgctg gtgctgccct
     3541 acacgggtgc ccatgacggc agcttcgcca cactcttccg agagctagac acgcggctgg
     3601 cggagctgag gctcactggc tacgggatct ccgacaccag cctcgaggag atcttcctga
     3661 aggtggtgga ggagtgtgct gcggacacag atatggagga tggcagctgc gggcagcacc
     3721 tatgcacagg cattgctggc ctagacgtaa ccctacggct caagatgccg ccacaggaga
     3781 cagcgctgga gaacggggaa ccagctgggt cagccccaga gactgaccag ggctctgggc
     3841 cagacgccgt gggccgggta cagggctggg cactgacccg ccagcagctc caggccctgc
     3901 ttctcaagcg ctttctgctt gcccgccgca gccgccgcgg cctgttcgcc cagtgaggac
     3961 gccccagggg accctggacg tgcccggctg ctcgaggcgc tgctgcagga ggcaggactg
     4021 gaggagcccc cagtgcagca
//
