LOCUS       XM_047438055            4352 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily A member 7
            (ABCA7), transcript variant X20, mRNA.
ACCESSION   XM_047438055
VERSION     XM_047438055.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4352
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..4352
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /note="ATP binding cassette subfamily A member 7; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 37 ESTs, 417 long SRA reads, 1 Protein, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 11 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
     CDS             108..4205
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /codon_start=1
                     /product="phospholipid-transporting ATPase ABCA7 isoform
                     X13"
                     /protein_id="XP_047294011.1"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
                     /translation="MEFSFSEELLVRTSAPQESSPLPHPAGPKGLEKRFPGSPQPALR
                     GLSLDFYQGHITAFLGHNGAGKTTTLSILSGLFPPSGGSAFILGHDVRSSMAAIRPHL
                     GVCPQYNVLFDMLTVDEHVWFYGRLKGLSAAVVGPEQDRLLQDVGLVSKQSVQTRHLS
                     GGMQRKLSVAIAFVGGSQVVILDEPTAGVDPASRRGIWELLLKYREGRTLILSTHHLD
                     EAELLGDRVAVVAGGRLCCCGSPLFLRRHLGSGYYLTLVKARLPLTTNEKADTDMEGS
                     VDTRQEKKNGSQGSRVGTPQLLALVQHWVPGARLVEELPHELVLVLPYTGAHDGSFAT
                     LFRELDTRLAELRLTGYGISDTSLEEIFLKVVEECAADTDMEDGSCGQHLCTGIAGLD
                     VTLRLKMPPQETALENGEPAGSAPETDQGSGPDAVGRVQGWALTRQQLQALLLKRFLL
                     ARRSRRGLFAQIVLPALFVGLALVFSLIVPPFGHYPALRLSPTMYGAQVSFFSEDAPG
                     DPGRARLLEALLQEAGLEEPPVQHSSHRFSAPEVPAEVAKVLASGNWTPESPSPACQC
                     SRPGARRLLPDCPAAAGGPPPPQAVTGSGEVVQNLTGRNLSDFLVKTYPRLVRQGLKT
                     KKWVNEVRYGGFSLGGRDPGLPSGQELGRSVEELWALLSPLPGGALDRVLKNLTAWAH
                     SLDAQDSLKIWFNNKGWHSMVAFVNRASNAILRAHLPPGPARHAHSITTLNHPLNLTK
                     EQLSEGALMASSVDVLVSICVVFAMSFVPASFTLVLIEERVTRAKHLQLMGGLSPTLY
                     WLGNFLWDMCNYLVPACIVVLIFLAFQQRAYVAPANLPALLLLLLLYGWSITPLMYPA
                     SFFFSVPSTAYVVLTCINLFIGINGSMATFVLELFSDQKLQEVSRILKQVFLIFPHFC
                     LGRGLIDMVRNQAMADAFERLGDRQFQSPLRWEVVGKNLLAMVIQGPLFLLFTLLLQH
                     RSQLLPQPRVRSLPLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVYRGQRMPAVD
                     RLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAREPSAAHLSM
                     GYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWYADRPAGTYS
                     GGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGRSVMLTSHSM
                     EECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPAAAFVAAEFP
                     GAELREAHGGRLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTMLEEVFLYFS
                     KDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAETVL"
ORIGIN      
        1 cccggcctac ggcagacgtc ttcagcctgg cccaggtctc tggccttctg ctgctggacg
       61 cggcgctcta cggcctcgcc acctggccag tacgggatcc ctgaaccatg gaattttcct
      121 tttcggagga gctactggtg cggacctcgg ccccccaaga gtccagcccc ttgccccacc
      181 ccgctggacc caaaggcctg gagaagcgct ttcctggaag cccgcagcca gccctgcggg
      241 ggctcagcct ggacttctac cagggccaca tcaccgcctt cctgggccac aacggggccg
      301 gcaagaccac caccctgtcc atcttgagtg gcctcttccc acccagtggt ggctctgcct
      361 tcatcctggg ccacgacgtc cgctccagca tggccgccat ccggccccac ctgggcgtct
      421 gtcctcagta caacgtgctg tttgacatgc tgaccgtgga cgagcacgtc tggttctatg
      481 ggcggctgaa gggtctgagt gccgctgtag tgggccccga gcaggaccgt ctgctgcagg
      541 atgtggggct ggtctccaag cagagtgtgc agactcgcca cctctctggt gggatgcaac
      601 ggaagctgtc cgtggccatt gcctttgtgg gcggctccca agttgttatc ctggacgagc
      661 ctacggctgg cgtggatcct gcttcccgcc gcggtatttg ggagctgctg ctcaaatacc
      721 gagaaggtcg cacgctgatc ctctccaccc accacctgga tgaggcagag ctgctgggag
      781 accgtgtggc cgtggtggca ggtggccgct tgtgctgctg tggctcccca ctcttcctgc
      841 gccgtcacct gggctccggc tactacctga cgctggtgaa ggcccgcctg cccctgacca
      901 ccaatgagaa ggctgacact gacatggagg gcagtgtgga caccaggcag gaaaagaaga
      961 atggcagcca gggcagcaga gtcggcactc ctcagctgct ggccctggta cagcactggg
     1021 tgcccggggc acggctggtg gaggagctgc cacacgagct ggtgctggtg ctgccctaca
     1081 cgggtgccca tgacggcagc ttcgccacac tcttccgaga gctagacacg cggctggcgg
     1141 agctgaggct cactggctac gggatctccg acaccagcct cgaggagatc ttcctgaagg
     1201 tggtggagga gtgtgctgcg gacacagata tggaggatgg cagctgcggg cagcacctat
     1261 gcacaggcat tgctggccta gacgtaaccc tacggctcaa gatgccgcca caggagacag
     1321 cgctggagaa cggggaacca gctgggtcag ccccagagac tgaccagggc tctgggccag
     1381 acgccgtggg ccgggtacag ggctgggcac tgacccgcca gcagctccag gccctgcttc
     1441 tcaagcgctt tctgcttgcc cgccgcagcc gccgcggcct gttcgcccag atcgtgctgc
     1501 ctgccctctt tgtgggcctg gccctcgtgt tcagcctcat cgtgcctcct ttcgggcact
     1561 acccggctct gcggctcagt cccaccatgt acggtgctca ggtgtccttc ttcagtgagg
     1621 acgccccagg ggaccctgga cgtgcccggc tgctcgaggc gctgctgcag gaggcaggac
     1681 tggaggagcc cccagtgcag catagctccc acaggttctc ggcaccagaa gttcctgctg
     1741 aagtggccaa ggtcttggcc agtggcaact ggaccccaga gtctccatcc ccagcctgcc
     1801 agtgtagccg gcccggtgcc cggcgcctgc tgcccgactg cccggctgca gctggtggtc
     1861 cccctccgcc ccaggcagtg accggctctg gggaagtggt tcagaacctg acaggccgga
     1921 acctgtctga cttcctggtc aagacctacc cgcgcctggt gcgccagggc ctgaagacta
     1981 agaagtgggt gaatgaggtc agatacggag gcttctcgct ggggggccga gacccaggcc
     2041 tgccctcggg ccaagagttg ggccgctcag tggaggagtt gtgggcgctg ctgagtcccc
     2101 tgcctggcgg ggccctcgac cgtgtcctga aaaacctcac agcctgggct cacagcctgg
     2161 atgctcagga cagtctcaag atctggttca acaacaaagg ctggcactcc atggtggcct
     2221 ttgtcaaccg agccagcaac gcaatcctcc gtgctcacct gcccccaggc ccggcccgcc
     2281 acgcccacag catcaccaca ctcaaccacc ccttgaacct caccaaggag cagctgtctg
     2341 agggtgcact gatggcctcc tcggtggacg tcctcgtctc catctgtgtg gtctttgcca
     2401 tgtcctttgt cccggccagc ttcactcttg tcctcattga ggagcgagtc acccgagcca
     2461 agcacctgca gctcatgggg ggcctgtccc ccaccctcta ctggcttggc aactttctct
     2521 gggacatgtg taactacttg gtgccagcat gcatcgtggt gctcatcttt ctggccttcc
     2581 agcagagggc atatgtggcc cctgccaacc tgcctgctct cctgctgttg ctactactgt
     2641 atggctggtc gatcacaccg ctcatgtacc cagcctcctt cttcttctcc gtgcccagca
     2701 cagcctatgt ggtgctcacc tgcataaacc tctttattgg catcaatgga agcatggcca
     2761 cctttgtgct tgagctcttc tctgatcaga agctgcagga ggtgagccgg atcttgaaac
     2821 aggtcttcct tatcttcccc cacttctgct tgggccgggg gctcattgac atggtgcgga
     2881 accaggccat ggctgatgcc tttgagcgct tgggagacag gcagttccag tcacccctgc
     2941 gctgggaggt ggtcggcaag aacctcttgg ccatggtgat acaggggccc ctcttccttc
     3001 tcttcacact actgctgcag caccgaagcc aactcctgcc acagcccagg gtgaggtctc
     3061 tgccactcct gggagaggag gacgaggatg tagcccgtga acgggagcgg gtggtccaag
     3121 gagccaccca gggggatgtg ttggtgctga ggaacttgac caaggtatac cgtgggcaga
     3181 ggatgccagc tgttgaccgc ttgtgcctgg ggattccccc tggtgagtgt tttgggctgc
     3241 tgggtgtgaa tggagcaggg aagacgtcca cgtttcgcat ggtgacgggg gacacattgg
     3301 ccagcagggg cgaggctgtg ctggcaggcc acagcgtggc ccgggaaccc agtgctgcgc
     3361 acctcagcat gggatactgc cctcaatccg atgccatctt tgagctgctg acgggccgcg
     3421 agcacctgga gctgcttgcg cgcctgcgcg gtgtcccgga ggcccaggtt gcccagaccg
     3481 ctggctcggg cctggcgcgt ctgggactct catggtacgc agaccggcct gcaggcacct
     3541 acagcggagg gaacaaacgc aagctggcga cggccctggc gctggttggg gacccagccg
     3601 tggtgtttct ggacgagccg accacaggca tggaccccag cgcgcggcgc ttcctttgga
     3661 acagcctttt ggccgtggtg cgggagggcc gttcagtgat gctcacctcc catagcatgg
     3721 aggagtgtga agcgctctgc tcgcgcctgg ccatcatggt gaatgggcgg ttccgctgcc
     3781 tgggcagccc gcaacatctc aagggcagat tcgcggcggg tcacacactg accctgcggg
     3841 tgcccgccgc aaggtcccag ccggcagcgg ccttcgtggc ggccgagttc cctggggcgg
     3901 agctgcgcga ggcacatgga ggccgcctgc gcttccagct gccgccggga gggcgctgcg
     3961 ccctggcgcg cgtctttgga gagctggcgg tgcacggcgc agagcacggc gtggaggact
     4021 tttccgtgag ccagacgatg ctggaggagg tattcttgta cttctccaag gaccagggga
     4081 aggacgagga caccgaagag cagaaggagg caggagtggg agtggacccc gcgccaggcc
     4141 tgcagcaccc caaacgcgtc agccagttcc tcgatgaccc tagcactgcc gagactgtgc
     4201 tctgagcctc cctcccctgc ggggccgcgg ggaggccctg ggaatggcaa gggcaaggta
     4261 gagtgcctag gagccctgga ctcaggctgg cagaggggct ggtgccctgg agaaaataaa
     4321 gagaaggctg gagagaagcc gtggtggtga aa
//
