LOCUS       XM_047438046            6631 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens ATP binding cassette subfamily A member 7
            (ABCA7), transcript variant X4, mRNA.
ACCESSION   XM_047438046
VERSION     XM_047438046.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000019.10) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6631
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="19"
     gene            1..6631
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /note="ATP binding cassette subfamily A member 7; Derived
                     by automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 2 mRNAs, 44 ESTs, 277 long SRA reads, 3 Proteins, and
                     100% coverage of the annotated genomic feature by RNAseq
                     alignments, including 6 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
     CDS             98..6484
                     /gene="ABCA7"
                     /gene_synonym="ABCA-SSN; ABCX; AD9"
                     /codon_start=1
                     /product="phospholipid-transporting ATPase ABCA7 isoform
                     X3"
                     /protein_id="XP_047294002.1"
                     /db_xref="GeneID:10347"
                     /db_xref="HGNC:HGNC:37"
                     /db_xref="MIM:605414"
                     /translation="MAFWTQLMLLLWKNFMYRRRQPVQLLVELLWPLFLFFILVAVRH
                     SHPPLEHHECHFPNKPLPSAGTVPWLQGLICNVNNTCFPQLTPGEEPGRLSNFNDSLV
                     SRLLADARTVLGGASAHRTLAGLGKLIATLRAARSTAQPQPTKQSPLEPPMLDVAELL
                     TSLLRTESLGLALGQAQEPLHSLLEAAEDLAQELLALRSLVELRALLQRPRGTSGPLE
                     LLSEALCSVRGPSSTVGPSLNWYEASDLMELVGQEPESALPDSSLSPACSELIGALDS
                     HPLSRLLWRRLKPLILGKLLFAPDTPFTRKLMAQVNRTFEELTLLRDVREVWEMLGPR
                     IFTFMNDSSNVAMLQRLLQMQDEGRRQPRPGGRDHMEALRSFLDPGSGGYSWQDAHAD
                     VGHLVGTLGRVTECLSLDKLEAAPSEAALVSRALQLLAEHRFWAGVVFLGPEDSSDPT
                     EHPTPDLGPGHVRIKIRMDIDVVTRTNKIRDRFWDPGPAADPLTDLRYVWGGFVYLQD
                     LVERAAVRVLSGANPRAGLYLQQMPYPCYVDDVFLRVLSRSLPLFLTLAWIYSVTLTV
                     KAVVREKETRLRDTMRAMGLSRAVLWLGWFLSCLGPFLLSAALLVLVLKLGDILPYSH
                     PGVVFLFLAAFAVATVTQSFLLSAFFSRANLAAACGGLAYFSLYLPYVLCVAWRDRLP
                     AGGRVAASLLSPVAFGFGCESLALLEEQGEGAQWHNVGTRPTADVFSLAQVSGLLLLD
                     AALYGLATWYLEAVCPGQYGIPEPWNFPFRRSYWCGPRPPKSPAPCPTPLDPKVLVEE
                     APPGLSPGVSVRSLEKRFPGSPQPALRGLSLDFYQGHITAFLGHNGAGKTTTLSILSG
                     LFPPSGGSAFILGHDVRSSMAAIRPHLGVCPQYNVLFDMLTVDEHVWFYGRLKGLSAA
                     VVGPEQDRLLQDVGLVSKQSVQTRHLSGGMQRKLSVAIAFVGGSQVVILDEPTAGVDP
                     ASRRGIWELLLKYREGRTLILSTHHLDEAELLGDRVAVVAGGRLCCCGSPLFLRRHLG
                     SGYYLTLVKARLPLTTNEKADTDMEGSVDTRQEKKNGSQGSRVGTPQLLALVQHWVPG
                     ARLVEELPHELVLVLPYTGAHDGSFATLFRELDTRLAELRLTGYGISDTSLEEIFLKV
                     VEECAADTDMEDGSCGQHLCTGIAGLDVTLRLKMPPQETALENGEPAGSAPETDQGSG
                     PDAVGRVQGWALTRQQLQALLLKRFLLARRSRRGLFAQIVLPALFVGLALVFSLIVPP
                     FGHYPALRLSPTMYGAQVSFFSEDAPGDPGRARLLEALLQEAGLEEPPVQHSSHRFSA
                     PEVPAEVAKVLASGNWTPESPSPACQCSRPGARRLLPDCPAAAGGPPPPQAVTGSGEV
                     VQNLTGRNLSDFLVKTYPRLVRQGLKTKKWVNEVRYGGFSLGGRDPGLPSGQELGRSV
                     EELWALLSPLPGGALDRVLKNLTAWAHSLDAQDSLKIWFNNKGWHSMVAFVNRASNAI
                     LRAHLPPGPARHAHSITTLNHPLNLTKEQLSEGALMASSVDVLVSICVVFAMSFVPAS
                     FTLVLIEERVTRAKHLQLMGGLSPTLYWLGNFLWDMCNYLVPACIVVLIFLAFQQRAY
                     VAPANLPALLLLLLLYGTAYVVLTCINLFIGINGSMATFVLELFSDQKLQEVSRILKQ
                     VFLIFPHFCLGRGLIDMVRNQAMADAFERLGDRQFQSPLRWEVVGKNLLAMVIQGPLF
                     LLFTLLLQHRSQLLPQPRVRSLPLLGEEDEDVARERERVVQGATQGDVLVLRNLTKVY
                     RGQRMPAVDRLCLGIPPGECFGLLGVNGAGKTSTFRMVTGDTLASRGEAVLAGHSVAR
                     EPSAAHLSMGYCPQSDAIFELLTGREHLELLARLRGVPEAQVAQTAGSGLARLGLSWY
                     ADRPAGTYSGGNKRKLATALALVGDPAVVFLDEPTTGMDPSARRFLWNSLLAVVREGR
                     SVMLTSHSMEECEALCSRLAIMVNGRFRCLGSPQHLKGRFAAGHTLTLRVPAARSQPA
                     AAFVAAEFPGAELREAHGGRLRFQLPPGGRCALARVFGELAVHGAEHGVEDFSVSQTM
                     LEEVFLYFSKDQGKDEDTEEQKEAGVGVDPAPGLQHPKRVSQFLDDPSTAETVL"
ORIGIN      
        1 aagctcagcg cacttggctt aaggggcggc gcgctccctg cctgctgctg ggcggaggga
       61 aggcggcaag agctgcggag cccctggaag tctcaccatg gccttctgga cacagctgat
      121 gctgctgctc tggaagaatt tcatgtatcg ccggagacag ccggtccagc tcctggtcga
      181 attgctgtgg cctctcttcc tcttcttcat cctggtggct gttcgccact cccacccgcc
      241 cctggagcac catgaatgcc acttcccaaa caagccactg ccatcggcgg gcaccgtgcc
      301 ctggctccag ggtctcatct gtaatgtgaa caacacctgc tttccgcagc tgacaccggg
      361 cgaggagccc gggcgcctga gcaacttcaa cgactccctg gtctcccggc tgctagccga
      421 tgcccgcact gtgctgggag gggccagtgc ccacaggacg ctggctggcc tagggaagct
      481 gatcgccacg ctgagggctg cacgcagcac ggcccagcct caaccaacca agcagtctcc
      541 actggaacca cccatgctgg atgtcgcgga gctgctgacg tcactgctgc gcacggaatc
      601 cctggggttg gcactgggcc aagcccagga gcccttgcac agcttgttgg aggccgctga
      661 ggacctggcc caggagctcc tggcgctgcg cagcctggtg gagcttcggg cactgctgca
      721 gagaccccga gggaccagcg gccccctgga gttgctgtca gaggccctct gcagtgtcag
      781 gggacctagc agcacagtgg gcccctccct caactggtac gaggctagtg acctgatgga
      841 gctggtgggg caggagccag aatccgccct gccagacagc agcctgagcc ccgcctgctc
      901 ggagctgatt ggagccctgg acagccaccc gctgtcccgc ctgctctgga gacgcctgaa
      961 gcctctgatc ctcgggaagc tactctttgc accagataca ccttttaccc ggaagctcat
     1021 ggcccaggtg aaccggacct tcgaggagct caccctgctg agggatgtcc gggaggtgtg
     1081 ggagatgctg ggaccccgga tcttcacctt catgaacgac agttccaatg tggccatgct
     1141 gcagcggctc ctgcagatgc aggatgaagg aagaaggcag cccagacctg gaggccggga
     1201 ccacatggag gccctgcgat cctttctgga ccctgggagc ggtggctaca gctggcagga
     1261 cgcacacgct gatgtggggc acctggtggg cacgctgggc cgagtgacgg agtgcctgtc
     1321 cttggacaag ctggaggcgg caccctcaga ggcagccctg gtgtcgcggg ccctgcaact
     1381 gctcgcggaa catcgattct gggccggcgt cgtcttcttg ggacctgagg actcttcaga
     1441 ccccacagag cacccaaccc cagacctggg ccccggccac gtgcgcatca aaatccgcat
     1501 ggacattgac gtggtcacga ggaccaataa gatcagggac aggttttggg accctggccc
     1561 agccgcggac cccctgaccg acctgcgcta cgtgtggggc ggcttcgtgt acctgcaaga
     1621 cctggtggag cgtgcagccg tccgcgtgct cagcggcgcc aacccccggg ccggcctcta
     1681 cctgcagcag atgccctatc cgtgctatgt ggacgacgtg ttcctgcgtg tgctgagccg
     1741 gtcgctgccg ctcttcctga cgctggcctg gatctactcc gtgacactga cagtgaaggc
     1801 cgtggtgcgg gagaaggaga cgcggctgcg ggacaccatg cgcgccatgg ggctcagccg
     1861 cgcggtgctc tggctaggct ggttcctcag ctgcctcggg cccttcctgc tcagcgccgc
     1921 actgctggtt ctggtgctca agctgggaga catcctcccc tacagccacc cgggcgtggt
     1981 cttcctgttc ttggcagcct tcgcggtggc cacggtgacc cagagcttcc tgctcagcgc
     2041 cttcttctcc cgcgccaacc tggctgcggc ctgcggcggc ctggcctact tctccctcta
     2101 cctgccctac gtgctgtgtg tggcttggcg ggaccggctg cccgcgggtg gccgcgtggc
     2161 cgcgagcctg ctgtcgcccg tggccttcgg cttcggctgc gagagcctgg ctctgctgga
     2221 ggagcagggc gagggcgcgc agtggcacaa cgtgggcacc cggcctacgg cagacgtctt
     2281 cagcctggcc caggtctctg gccttctgct gctggacgcg gcgctctacg gcctcgccac
     2341 ctggtacctg gaagctgtgt gcccaggcca gtacgggatc cctgaaccat ggaattttcc
     2401 ttttcggagg agctactggt gcggacctcg gccccccaag agtccagccc cttgccccac
     2461 cccgctggac ccaaaggtgc tggtagaaga ggcaccgccc ggcctgagtc ctggcgtctc
     2521 cgttcgcagc ctggagaagc gctttcctgg aagcccgcag ccagccctgc gggggctcag
     2581 cctggacttc taccagggcc acatcaccgc cttcctgggc cacaacgggg ccggcaagac
     2641 caccaccctg tccatcttga gtggcctctt cccacccagt ggtggctctg ccttcatcct
     2701 gggccacgac gtccgctcca gcatggccgc catccggccc cacctgggcg tctgtcctca
     2761 gtacaacgtg ctgtttgaca tgctgaccgt ggacgagcac gtctggttct atgggcggct
     2821 gaagggtctg agtgccgctg tagtgggccc cgagcaggac cgtctgctgc aggatgtggg
     2881 gctggtctcc aagcagagtg tgcagactcg ccacctctct ggtgggatgc aacggaagct
     2941 gtccgtggcc attgcctttg tgggcggctc ccaagttgtt atcctggacg agcctacggc
     3001 tggcgtggat cctgcttccc gccgcggtat ttgggagctg ctgctcaaat accgagaagg
     3061 tcgcacgctg atcctctcca cccaccacct ggatgaggca gagctgctgg gagaccgtgt
     3121 ggccgtggtg gcaggtggcc gcttgtgctg ctgtggctcc ccactcttcc tgcgccgtca
     3181 cctgggctcc ggctactacc tgacgctggt gaaggcccgc ctgcccctga ccaccaatga
     3241 gaaggctgac actgacatgg agggcagtgt ggacaccagg caggaaaaga agaatggcag
     3301 ccagggcagc agagtcggca ctcctcagct gctggccctg gtacagcact gggtgcccgg
     3361 ggcacggctg gtggaggagc tgccacacga gctggtgctg gtgctgccct acacgggtgc
     3421 ccatgacggc agcttcgcca cactcttccg agagctagac acgcggctgg cggagctgag
     3481 gctcactggc tacgggatct ccgacaccag cctcgaggag atcttcctga aggtggtgga
     3541 ggagtgtgct gcggacacag atatggagga tggcagctgc gggcagcacc tatgcacagg
     3601 cattgctggc ctagacgtaa ccctacggct caagatgccg ccacaggaga cagcgctgga
     3661 gaacggggaa ccagctgggt cagccccaga gactgaccag ggctctgggc cagacgccgt
     3721 gggccgggta cagggctggg cactgacccg ccagcagctc caggccctgc ttctcaagcg
     3781 ctttctgctt gcccgccgca gccgccgcgg cctgttcgcc cagatcgtgc tgcctgccct
     3841 ctttgtgggc ctggccctcg tgttcagcct catcgtgcct cctttcgggc actacccggc
     3901 tctgcggctc agtcccacca tgtacggtgc tcaggtgtcc ttcttcagtg aggacgcccc
     3961 aggggaccct ggacgtgccc ggctgctcga ggcgctgctg caggaggcag gactggagga
     4021 gcccccagtg cagcatagct cccacaggtt ctcggcacca gaagttcctg ctgaagtggc
     4081 caaggtcttg gccagtggca actggacccc agagtctcca tccccagcct gccagtgtag
     4141 ccggcccggt gcccggcgcc tgctgcccga ctgcccggct gcagctggtg gtccccctcc
     4201 gccccaggca gtgaccggct ctggggaagt ggttcagaac ctgacaggcc ggaacctgtc
     4261 tgacttcctg gtcaagacct acccgcgcct ggtgcgccag ggcctgaaga ctaagaagtg
     4321 ggtgaatgag gtcagatacg gaggcttctc gctggggggc cgagacccag gcctgccctc
     4381 gggccaagag ttgggccgct cagtggagga gttgtgggcg ctgctgagtc ccctgcctgg
     4441 cggggccctc gaccgtgtcc tgaaaaacct cacagcctgg gctcacagcc tggatgctca
     4501 ggacagtctc aagatctggt tcaacaacaa aggctggcac tccatggtgg cctttgtcaa
     4561 ccgagccagc aacgcaatcc tccgtgctca cctgccccca ggcccggccc gccacgccca
     4621 cagcatcacc acactcaacc accccttgaa cctcaccaag gagcagctgt ctgagggtgc
     4681 actgatggcc tcctcggtgg acgtcctcgt ctccatctgt gtggtctttg ccatgtcctt
     4741 tgtcccggcc agcttcactc ttgtcctcat tgaggagcga gtcacccgag ccaagcacct
     4801 gcagctcatg gggggcctgt cccccaccct ctactggctt ggcaactttc tctgggacat
     4861 gtgtaactac ttggtgccag catgcatcgt ggtgctcatc tttctggcct tccagcagag
     4921 ggcatatgtg gcccctgcca acctgcctgc tctcctgctg ttgctactac tgtatggcac
     4981 agcctatgtg gtgctcacct gcataaacct ctttattggc atcaatggaa gcatggccac
     5041 ctttgtgctt gagctcttct ctgatcagaa gctgcaggag gtgagccgga tcttgaaaca
     5101 ggtcttcctt atcttccccc acttctgctt gggccggggg ctcattgaca tggtgcggaa
     5161 ccaggccatg gctgatgcct ttgagcgctt gggagacagg cagttccagt cacccctgcg
     5221 ctgggaggtg gtcggcaaga acctcttggc catggtgata caggggcccc tcttccttct
     5281 cttcacacta ctgctgcagc accgaagcca actcctgcca cagcccaggg tgaggtctct
     5341 gccactcctg ggagaggagg acgaggatgt agcccgtgaa cgggagcggg tggtccaagg
     5401 agccacccag ggggatgtgt tggtgctgag gaacttgacc aaggtatacc gtgggcagag
     5461 gatgccagct gttgaccgct tgtgcctggg gattccccct ggtgagtgtt ttgggctgct
     5521 gggtgtgaat ggagcaggga agacgtccac gtttcgcatg gtgacggggg acacattggc
     5581 cagcaggggc gaggctgtgc tggcaggcca cagcgtggcc cgggaaccca gtgctgcgca
     5641 cctcagcatg ggatactgcc ctcaatccga tgccatcttt gagctgctga cgggccgcga
     5701 gcacctggag ctgcttgcgc gcctgcgcgg tgtcccggag gcccaggttg cccagaccgc
     5761 tggctcgggc ctggcgcgtc tgggactctc atggtacgca gaccggcctg caggcaccta
     5821 cagcggaggg aacaaacgca agctggcgac ggccctggcg ctggttgggg acccagccgt
     5881 ggtgtttctg gacgagccga ccacaggcat ggaccccagc gcgcggcgct tcctttggaa
     5941 cagccttttg gccgtggtgc gggagggccg ttcagtgatg ctcacctccc atagcatgga
     6001 ggagtgtgaa gcgctctgct cgcgcctggc catcatggtg aatgggcggt tccgctgcct
     6061 gggcagcccg caacatctca agggcagatt cgcggcgggt cacacactga ccctgcgggt
     6121 gcccgccgca aggtcccagc cggcagcggc cttcgtggcg gccgagttcc ctggggcgga
     6181 gctgcgcgag gcacatggag gccgcctgcg cttccagctg ccgccgggag ggcgctgcgc
     6241 cctggcgcgc gtctttggag agctggcggt gcacggcgca gagcacggcg tggaggactt
     6301 ttccgtgagc cagacgatgc tggaggaggt attcttgtac ttctccaagg accaggggaa
     6361 ggacgaggac accgaagagc agaaggaggc aggagtggga gtggaccccg cgccaggcct
     6421 gcagcacccc aaacgcgtca gccagttcct cgatgaccct agcactgccg agactgtgct
     6481 ctgagcctcc ctcccctgcg gggccgcggg gaggccctgg gaatggcaag ggcaaggtag
     6541 agtgcctagg agccctggac tcaggctggc agaggggctg gtgccctgga gaaaataaag
     6601 agaaggctgg agagaagccg tggtggtgaa a
//
