LOCUS       XM_047419711            1564 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens aminoadipate-semialdehyde synthase (AASS),
            transcript variant X5, mRNA.
ACCESSION   XM_047419711
VERSION     XM_047419711.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1564
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..1564
                     /gene="AASS"
                     /gene_synonym="LKR/SDH; LKRSDH; LORSDH"
                     /note="aminoadipate-semialdehyde synthase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 18 ESTs, 87 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     56 samples with support for all annotated introns"
                     /db_xref="GeneID:10157"
                     /db_xref="HGNC:HGNC:17366"
                     /db_xref="MIM:605113"
     CDS             105..1514
                     /gene="AASS"
                     /gene_synonym="LKR/SDH; LKRSDH; LORSDH"
                     /codon_start=1
                     /product="alpha-aminoadipic semialdehyde synthase,
                     mitochondrial isoform X3"
                     /protein_id="XP_047275667.1"
                     /db_xref="GeneID:10157"
                     /db_xref="HGNC:HGNC:17366"
                     /db_xref="MIM:605113"
                     /translation="MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAP
                     KHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMS
                     RKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMI
                     NILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLT
                     FVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTD
                     AVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKF
                     SPAGVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEG
                     SGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDGTCS
                     VTFNGHQEKGFGSWIWLHI"
ORIGIN      
        1 agtttcttct aggaattcgg agcctcccct gcagcgactc ggaagattcg aggcggcggg
       61 ggacaagtcg gcgccccaga gcggacgagt caccaggtgt caagatgctg caagtacata
      121 ggactggact gggcaggctg ggggtcagcc tctccaaggg tcttcaccac aaagctgtgt
      181 tggccgtccg gagggaggat gtgaacgcct gggagagaag ggccccgcta gctcccaagc
      241 acatcaaagg catcaccaat ctgggataca aggtcttgat acagccttcg aatcggcggg
      301 ccattcatga taaggactat gtcaaagctg gtggcattct tcaggaggat atttctgaag
      361 cttgtctaat tttaggagtt aaaagacctc cagaggaaaa attaatgtcc aggaagactt
      421 atgcattttt ctcccacaca ataaaagctc aggaggccaa tatgggcttg ttggatgaga
      481 ttctaaaaca ggaaattcgc cttattgatt atgagaaaat ggtggatcat agaggagtac
      541 gggtagtggc atttggacag tgggctggtg tggcaggaat gatcaacatt ttacatggaa
      601 tgggtttaag gctccttgct ttgggacatc acacaccttt tatgcacatt ggcatggctc
      661 ataactacag gaatagcagt caggctgtgc aagctgtccg tgatgctggc tatgaaatat
      721 ctttgggttt gatgcctaag tcaataggac ccttaacatt tgtgttcaca ggaactggta
      781 atgtttctaa gggagcccaa gcaatcttta atgagctacc ttgtgaatat gtggagcccc
      841 atgaattaaa agaagtttcc caaactggag acctcagaaa agtgtatggg acggtgttaa
      901 gtcgtcatca tcatcttgtc aggaaaacag atgctgtgta tgatcctgca gagtatgaca
      961 aacatccgga gcgctacata agtcgtttta atactgatat tgcaccctat acaacttgct
     1021 taattaatgg aatctactgg gaacaaaaca ctcctcgcct cctaacccgc caagatgctc
     1081 agagtctcct ggctccgggc aagttctcac ctgctggtgt ggaaggctgc cctgcattac
     1141 cacacaaact cgtggcaata tgtgacattt cagctgacac aggagggtct atagagttta
     1201 tgactgagtg tacaacaata gagcatccct tttgcatgta tgatgcagac cagcatatta
     1261 ttcatgacag tgttgaaggc tcggggatcc tgatgtgttc cattgacaat ttgccggcac
     1321 agctcccaat tgaagctaca gaatgctttg gagacatgct ttacccttat gttgaagaaa
     1381 tgatattatc agacgcgaca cagcctcttg aaagtcagaa tttttctcct gtggtgagag
     1441 atggaacgtg ctcagtcact ttcaatgggc accaggagaa aggttttggt tcttggatct
     1501 ggctacatat ctgagcctgt attagaatat ttatcaagag atggcaatat agaaataaca
     1561 gtag
//
