LOCUS       XM_047419710            2677 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens aminoadipate-semialdehyde synthase (AASS),
            transcript variant X2, mRNA.
ACCESSION   XM_047419710
VERSION     XM_047419710.1
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000007.14) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="7"
     gene            1..2677
                     /gene="AASS"
                     /gene_synonym="LKR/SDH; LKRSDH; LORSDH"
                     /note="aminoadipate-semialdehyde synthase; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 22 ESTs, 241 long SRA reads, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     53 samples with support for all annotated introns"
                     /db_xref="GeneID:10157"
                     /db_xref="HGNC:HGNC:17366"
                     /db_xref="MIM:605113"
     CDS             105..2507
                     /gene="AASS"
                     /gene_synonym="LKR/SDH; LKRSDH; LORSDH"
                     /codon_start=1
                     /product="alpha-aminoadipic semialdehyde synthase,
                     mitochondrial isoform X2"
                     /protein_id="XP_047275666.1"
                     /db_xref="GeneID:10157"
                     /db_xref="HGNC:HGNC:17366"
                     /db_xref="MIM:605113"
                     /translation="MLQVHRTGLGRLGVSLSKGLHHKAVLAVRREDVNAWERRAPLAP
                     KHIKGITNLGYKVLIQPSNRRAIHDKDYVKAGGILQEDISEACLILGVKRPPEEKLMS
                     RKTYAFFSHTIKAQEANMGLLDEILKQEIRLIDYEKMVDHRGVRVVAFGQWAGVAGMI
                     NILHGMGLRLLALGHHTPFMHIGMAHNYRNSSQAVQAVRDAGYEISLGLMPKSIGPLT
                     FVFTGTGNVSKGAQAIFNELPCEYVEPHELKEVSQTGDLRKVYGTVLSRHHHLVRKTD
                     AVYDPAEYDKHPERYISRFNTDIAPYTTCLINGIYWEQNTPRLLTRQDAQSLLAPGKF
                     SPAGVEGCPALPHKLVAICDISADTGGSIEFMTECTTIEHPFCMYDADQHIIHDSVEG
                     SGILMCSIDNLPAQLPIEATECFGDMLYPYVEEMILSDATQPLESQNFSPVVRDAVIT
                     SNGTLPDKYKYIQTLRESRERAQSLSMGTRRKVLVLGSGYISEPVLEYLSRDGNIEIT
                     VGSDMKNQIEQLGKKYNINPVSMDICKQEEKLGFLVAKQDLVISLLPYVLHPLVAKAC
                     ITNKVNMVTASYITPALKELEKSVEDAGITIIGELGLDPGLDHMLAMETIDKAKEVGA
                     TIESYISYCGGLPAPEHSNNPLRYKFSWSPVGVLMNVMQSATYLLDGKVVNVAGGISF
                     LDAVTSMDFFPGLNLEGYPNRDSTKYAEIYGISSAHTLLRGTLRYKGYMKALNGFVKL
                     GLINREALPAFRPEANPLTWKQLLCDLVGISPSSEHDVLKEAVLKKLGGDNTQLEAAE
                     WS"
ORIGIN      
        1 agtttcttct aggaattcgg agcctcccct gcagcgactc ggaagattcg aggcggcggg
       61 ggacaagtcg gcgccccaga gcggacgagt caccaggtgt caagatgctg caagtacata
      121 ggactggact gggcaggctg ggggtcagcc tctccaaggg tcttcaccac aaagctgtgt
      181 tggccgtccg gagggaggat gtgaacgcct gggagagaag ggccccgcta gctcccaagc
      241 acatcaaagg catcaccaat ctgggataca aggtcttgat acagccttcg aatcggcggg
      301 ccattcatga taaggactat gtcaaagctg gtggcattct tcaggaggat atttctgaag
      361 cttgtctaat tttaggagtt aaaagacctc cagaggaaaa attaatgtcc aggaagactt
      421 atgcattttt ctcccacaca ataaaagctc aggaggccaa tatgggcttg ttggatgaga
      481 ttctaaaaca ggaaattcgc cttattgatt atgagaaaat ggtggatcat agaggagtac
      541 gggtagtggc atttggacag tgggctggtg tggcaggaat gatcaacatt ttacatggaa
      601 tgggtttaag gctccttgct ttgggacatc acacaccttt tatgcacatt ggcatggctc
      661 ataactacag gaatagcagt caggctgtgc aagctgtccg tgatgctggc tatgaaatat
      721 ctttgggttt gatgcctaag tcaataggac ccttaacatt tgtgttcaca ggaactggta
      781 atgtttctaa gggagcccaa gcaatcttta atgagctacc ttgtgaatat gtggagcccc
      841 atgaattaaa agaagtttcc caaactggag acctcagaaa agtgtatggg acggtgttaa
      901 gtcgtcatca tcatcttgtc aggaaaacag atgctgtgta tgatcctgca gagtatgaca
      961 aacatccgga gcgctacata agtcgtttta atactgatat tgcaccctat acaacttgct
     1021 taattaatgg aatctactgg gaacaaaaca ctcctcgcct cctaacccgc caagatgctc
     1081 agagtctcct ggctccgggc aagttctcac ctgctggtgt ggaaggctgc cctgcattac
     1141 cacacaaact cgtggcaata tgtgacattt cagctgacac aggagggtct atagagttta
     1201 tgactgagtg tacaacaata gagcatccct tttgcatgta tgatgcagac cagcatatta
     1261 ttcatgacag tgttgaaggc tcggggatcc tgatgtgttc cattgacaat ttgccggcac
     1321 agctcccaat tgaagctaca gaatgctttg gagacatgct ttacccttat gttgaagaaa
     1381 tgatattatc agacgcgaca cagcctcttg aaagtcagaa tttttctcct gtggtgagag
     1441 atgcagtgat tacatccaac ggtacattac ctgataaata taaatatatc cagacactcc
     1501 gggagagcag ggaacgtgct cagtcacttt caatgggcac caggagaaag gttttggttc
     1561 ttggatctgg ctacatatct gagcctgtat tagaatattt atcaagagat ggcaatatag
     1621 aaataacagt aggatctgac atgaagaatc aaattgaaca gttaggcaag aaatataata
     1681 ttaatcctgt tagcatggac atttgtaaac aagaagagaa gctgggcttc ttggtggcaa
     1741 aacaggatct tgtcatcagc ttgttgcctt atgtattgca ccctcttgtg gccaaggcct
     1801 gcatcacaaa caaagttaac atggtcactg caagctacat cacaccagca ctaaaagaat
     1861 tggaaaagag tgtggaagat gctggcatca caatcattgg tgaattggga ttggaccctg
     1921 gtctggatca catgttagca atggaaacaa tagataaagc caaggaagtg ggagccacga
     1981 ttgaatcata tatttcctac tgtggtgggc ttccagcccc tgaacattca aacaatccat
     2041 tgagatataa atttagctgg agtccagtgg gagttttgat gaatgtaatg cagtctgcca
     2101 cctatctgct cgatggaaag gttgtgaatg ttgcaggagg catctccttt cttgatgccg
     2161 ttacgtccat ggattttttt ccaggattaa atttggaagg ctatcctaac agagacagta
     2221 cgaaatatgc tgagatttat ggcatttctt ctgctcacac tttgttgcgg gggacactga
     2281 gatataaggg atatatgaaa gctttgaatg gatttgtaaa attaggtctt ataaacagag
     2341 aagcgcttcc tgcctttaga cctgaggcca accctctcac ctggaaacaa ctcctctgtg
     2401 acctagttgg gatttcaccc tcctctgagc atgatgtgtt gaaggaagct gttcttaaga
     2461 aactaggagg agacaatacc cagttggagg ctgctgaatg gtcctgaaga aaaagatatg
     2521 attgtgatga gagacagctt tggaatcaga catccttctg gacatttaga acataaaacg
     2581 attgatcttg tggcttatgg ggacatcaat ggcttttcag ccatggctaa aaccgtgggg
     2641 ttacccaccg ccatggcagc caaaatgttg cttgatg
//
