LOCUS       XM_017028831            2470 bp    mRNA    linear   PRI 25-AUG-2024
DEFINITION  PREDICTED: Homo sapiens alpha 1,4-galactosyltransferase (P1PK blood
            group) (A4GALT), transcript variant X6, mRNA.
ACCESSION   XM_017028831
VERSION     XM_017028831.2
DBLINK      BioProject: PRJNA168
KEYWORDS    RefSeq.
SOURCE      Homo sapiens (human)
  ORGANISM  Homo sapiens
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini;
            Catarrhini; Hominidae; Homo.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_000022.11) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            On Apr 5, 2022 this sequence version replaced XM_017028831.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_000001405.40-RS_2024_08
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.3
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           RefSeqFE; cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 08/23/2024
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2470
                     /organism="Homo sapiens"
                     /mol_type="mRNA"
                     /db_xref="taxon:9606"
                     /chromosome="22"
     gene            1..2470
                     /gene="A4GALT"
                     /gene_synonym="A14GALT; A4GALT1; Gb3S; P(k); P1; P1PK; PK"
                     /note="alpha 1,4-galactosyltransferase (P1PK blood group);
                     Derived by automated computational analysis using gene
                     prediction method: Gnomon. Supporting evidence includes
                     similarity to: 4 mRNAs, 9 ESTs, 164 long SRA reads, 3
                     Proteins, and 99% coverage of the annotated genomic
                     feature by RNAseq alignments, including 15 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:53947"
                     /db_xref="HGNC:HGNC:18149"
                     /db_xref="MIM:607922"
     CDS             640..1701
                     /gene="A4GALT"
                     /gene_synonym="A14GALT; A4GALT1; Gb3S; P(k); P1; P1PK; PK"
                     /codon_start=1
                     /product="lactosylceramide 4-alpha-galactosyltransferase
                     isoform X1"
                     /protein_id="XP_016884320.1"
                     /db_xref="GeneID:53947"
                     /db_xref="HGNC:HGNC:18149"
                     /db_xref="MIM:607922"
                     /translation="MSKPPDLLLRLLRGAPRQRVCTLFIIGFKFTFFVSIMIYWHVVG
                     EPKEKGQLYNLPAEIPCPTLTPPTPPSHGPTPGNIFFLETSDRTNPNFLFMCSVESAA
                     RTHPESHVLVLMKGLPGGNASLPRHLGISLLSCFPNVQMLPLDLRELFRDTPLADWYA
                     AVQGRWEPYLLPVLSDASRIALMWKFGGIYLDTDFIVLKNLRNLTNVLGTQSRYVLNG
                     AFLAFERRHEFMALCMRDFVDHYNGWIWGHQGPQLLTRVFKKWCSIRSLAESRACRGV
                     TTLPPEAFYPIPWQDWKKYFEDINPEELPRLLSATYAVHVWNKKSQGTRFEATSRALL
                     AQLHARYCPTTHEAMKMYL"
ORIGIN      
        1 actgccctcc ggccgccgcg ccgcccgccc gccggggccc cgctgtccgc cgcccgccgc
       61 cgctggagct agagatggat ttgcagccgc tgcaagtgtg tggaagggcc gtgttcgtgt
      121 tggcaaagaa ggtcggctgc tgagccaggg cgtgtctccc ggaggcctgt gggctgccag
      181 gatccccacc tctctgcaat gggctgccca ggctggtcag ttaccagcca gtgacatcag
      241 cgaggttccc tgctctctac cctgggaagg gcccagccta agttaccaag ccccaggctc
      301 ccagtaccac cctcagccta tgtggattgc caccccacct tctgcctgtc cttgggaggg
      361 gaccgactct tagctcccct tagcaatcag gttgcaccca gtcccttgac tttatgccca
      421 ggtttcctgg cacctaaagt agaaacgatg caactgcccc tcgggcttgc tgagggtcaa
      481 agggggtgtg actttgtcat ggagcgtaga agtcagagtc gatggtgatc ccgctggctg
      541 ttaacatcga tacagttcag gtcagcatgc accaagttcc tccaacacac cagaccagcc
      601 ggttcctgct ggaagctcct ggtctgatct ggggatacca tgtccaagcc ccccgacctc
      661 ctgctgcggc tgctccgggg cgccccaagg cagcgggtct gcaccctgtt catcatcggc
      721 ttcaagttca cgtttttcgt ctccatcatg atctactggc acgttgtggg agagcccaag
      781 gagaaagggc agctctataa cctgccagca gagatcccct gccccacctt gacacccccc
      841 accccaccct cccacggccc cactccaggc aacatcttct tcctggagac ttcagaccgg
      901 accaacccca acttcctgtt catgtgctcg gtggagtcgg ccgccagaac tcaccccgaa
      961 tcccacgtgc tggtcctgat gaaagggctt ccgggtggca acgcctctct gccccggcac
     1021 ctgggcatct cacttctgag ctgcttcccg aatgtccaga tgctcccgct ggacctgcgg
     1081 gagctgttcc gggacacacc cctggccgac tggtacgcgg ccgtgcaggg gcgctgggag
     1141 ccctacctgc tgcccgtgct ctccgacgcc tccaggatcg cactcatgtg gaagttcggc
     1201 ggcatctacc tggacacgga cttcattgtt ctcaagaacc tgcggaacct gaccaacgtg
     1261 ctgggcaccc agtcccgcta cgtcctcaac ggcgcgttcc tggccttcga gcgccggcac
     1321 gagttcatgg cgctgtgcat gcgggacttc gtggaccact acaacggctg gatctggggt
     1381 caccagggcc cgcagctgct cacgcgggtc ttcaagaagt ggtgttccat ccgcagcctg
     1441 gccgagagcc gcgcctgccg cggcgtcacc accctgcccc ctgaggcctt ctaccccatc
     1501 ccctggcagg actggaagaa gtactttgag gacatcaacc ccgaggagct gccgcggctg
     1561 ctcagtgcca cctatgctgt ccacgtgtgg aacaagaaga gccagggcac gcggttcgag
     1621 gccacgtcca gggcactgct ggcccagctg catgcccgct actgccccac gacgcacgag
     1681 gccatgaaaa tgtacttgtg aggggcccgc caggtcacct ccccaacctg ctcctgatgg
     1741 ggcactgggc cgcccttccc ggggaggcaa gattgagggc ccgggagagg gaggcccgag
     1801 ctgccaccgg gcttaggcag gctgttgagg agctgtggga gcaggcccag tgggaggctg
     1861 tggacacccc gaggacagtg tcctgtctcg aggcagggct gacacatggt gccatagcca
     1921 gcggagggcg ctcagtgagt gccccgggcc ttctagacaa caggcaggaa ggatgaacct
     1981 cagggcaccc ccaggtggtg cggaaagcca ggcagttggg acagaggtgc ccacgagggc
     2041 agaggccggt gctaagggga tggggaagaa gggacaagat tcccagagag gagaggaggc
     2101 tgttggtagg aaagtggcag ggctggggga gacccagccc caagggtccg gggcggagga
     2161 tgctttgttc ttttctggtt ttggttcctc tttcgcgggg ggtgggggag gtcaacaggg
     2221 actgagtggg gcagaggccc agaagtgcca gcctggggag ccgtttgggg gcagcccctt
     2281 ctgcccaccc catccttctt cctctccaga gatgccaggg gggcgtgtat gctctgcccc
     2341 ttccctcaga caggggctgg gtggggaggc tctttaggct caggagaagc attttaaaga
     2401 aacccccacc ctgccgcccg cattataaac acaggagaat aatcaataga ataaaagtga
     2461 ccgactgtca
//
