The gene trap vector including the En2 intron and Beta-geo-SV40pA fell within intron 7 or 8 of the locus, depending on alternative splicing of exon 8. It was mapped to the middle of intron 7. Mutated CT45 ES cells containing this vector were used to generate mutant mice. (J:50092, J:96325)

Basic Information

Allele
Strain of Origin
Allele Type
Mutation
Inheritance
Related Gene
Related Disease
Reference
129P2/OlaHsd
Gene trapped
Insertion of gene trap vector
--
1
--
10

Phenotypes

Legend:
hm: homozygous
ht: heterozygous
cn: conditional genotype
cx: complex: > 1 genome feature
tg: involves transgenes
ot: other: hemizygous, indeterminate,...
(F): Female
(M): Male
phenotype observed
N: normal phenotype
(#): related diseases count
Phenotypes:
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Phenotypes

References Literature

Title
PMID
Journal
Year
IF
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